A natural freak would usually have been born with a genetic abnormality, while a self-made freak was a person who was altered artificially (with methods such as surgical implants).
freak 1 (frik) n. 1. an abnormal phenomenon or product or unusual object; anomaly. 2. a person or animal on exhibition as an example of a strange deviation from nature. 3. a sudden and apparently causeless change; caprice.
Synonyms for freak, when used to describe something or something abnormal, include anomaly, chimera, misshape, and oddity. Weirdo is slang for freak, and regular is its antonym.
There are 21 meanings listed in OED's entry for the word freak, two of which are labelled obsolete, and nine of which are considered offensive and derogatory. See ‘Meaning & use’ for definitions, usage, and quotation evidence.
An enthusiast, or person who has an obsession with, or extreme knowledge of, something. synonyms quotations Synonyms: fanatic, geek; see also Thesaurus: fan Bob's a real video-game freak. He owns every games console of the last ten years.
to become or make frightened, nervous, or wildly excited: The loud noise caused the horse to freak. freak out, [Slang.] to enter into or cause a period of irrational behavior or emotional instability, as under the influence of a drug: to be freaked out on LSD.
People are sometimes referred to as freaks when their behaviour or attitude is very different from that of the majority of people. If you refer to someone as a freak, you mean that they are physically abnormal in some way. This use could cause offence.