Stem cell therapy for degenerative intervertebral disk disease: Q …
Jun 23, 2017 · In collaboration with orthopedic and neurosurgery researchers, we are examining the epigenetics in identifying gene expression profiles associated with disk degeneration. The …
Gene therapy - Mayo Clinic
Apr 23, 2024 · Gene therapy aims to fix a faulty gene or replace it with a healthy gene to try to cure disease or make the body better able to fight disease. It holds promise as a treatment for …
Chemotherapy for breast cancer - Mayo Clinic
Jan 10, 2025 · Gene expression profiling tests, such as Oncotype DX, EndoPredict and MammaPrint, may help predict the risk of recurrence and give your doctor an idea of how your …
TERT expression may better predict meningioma behavior
Oct 7, 2025 · Researchers co-led by a Mayo Clinic Neurosurgery chair have demonstrated that telomerase reverse transcriptase (TERT) gene expression in meningiomas predicts earlier …
HER2-positive breast cancer: What is it? - Mayo Clinic
Apr 9, 2024 · HER2-positive breast cancer tends to be more aggressive than other types of breast cancer. Treatments that target HER2 are very effective.
Genomic testing expands options for melanoma staging
Nov 8, 2025 · A recent multicenter clinical trial based on research developed by Mayo Clinic experts provides valuable new insights into the management of early- and intermediate-stage …
mRNA transfection improves CTL response in immunotherapy
Apr 30, 2022 · Reduced NKG7 expression altered cytolytic granule number, trafficking and calcium release, resulting in decreased killing of tumor cells by CTLs. Transfection of CTLs …
Phase 1 clinical trial testing gene therapy treatment for knee ...
Oct 10, 2025 · Results demonstrate that injection of local gene therapy for knee joints is safe and achieves sustained, intra-articular concentrations of a therapeutic gene product.
Publications - Andrew L. Folpe, M.D. - Mayo Clinic
Malignant melanotic schwannian tumor: a clinicopathologic, immunohistochemical, and gene expression profiling study of 40 cases, with a proposal for the reclassification of "melanotic …
Breast cancer staging - Mayo Clinic
May 22, 2025 · Gene expression test results. Gene expression tests look for certain genes inside the cancer cells. The results can give the healthcare team a better idea of whether the cancer …